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Among the challenges of a pandemic is the need to scale up to billions of doses, at a larger scale than typically needed for vaccines, from raw materials all the way through to the materials for the containers for fill/finish. Having adequate raw materials, building and staffing the facilities, and tech transfer are all keys to success. [...]we can plug into existing infrastructure, including services (gas, water, waste, etc.) as well as analytics and quality labs." Emergent BioSolutions says that its flexible CDMO capacity deployment model can respond quickly to demand fluctuations. The company's facilities in France, Switzerland, and the US are working on the project;at CordenPharma Colorado, unique high-pressure chromatography systems usually used for manufacturing peptides have been reallocated for purifying lipids.
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Background: This study aims to evaluate the mental health status of children, adolescents and their parents during the first year of COVID-19 pandemic in Belgium. Method(s): Analysis compared results before and during the second national lockdown, which started on November 2nd 2020. A cross-sectional online survey was conducted between May 2020 and April 2021. Result(s): Two hundred and eighteen adults and 273 children fully completed the survey. Almost one in five children (17.9%) presented moderate-to-severe scores of depression. Adolescents presented a higher level of depression than children (p = 0.007). The rate of moderate-to-severe depression scores (10.8% to 21%, p = 0.007) and internalized symptoms increased during the second lockdown (p < 0.001). Parents' depression (p < 0.001) and anxiety (p = 0.027) levels also increased during the second lockdown. Logistic regression showed that the use of psychotropic medication in parents and parents' depression scores were risk factors for children to have worse depression scores. Conclusion(s): The second lockdown appears to worsen the effects of the pandemic on children's and parents' mental health. There is a need to implement specific interventions targeting both children/adolescents and their parents to support them during lockdown periods and improve mental health outcomes.Copyright © 2022, The Author(s).
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This research note presents the RepResent Belgian Panel (RBP). The RBP is a voter panel survey consisting of four waves fielded to a sample of voters in Belgium around the May 2019 federal, regional, and European elections in Belgium. It provides unique data on about 250 variables for a quota sample of the same respondents, pre-2019 elections (N = 7351), post-2019 elections (N = 3909), one year after the elections (N = 1996), and 2 years after the elections (N = 1119). The RBP panel dataset was designed to analyse voters' political attitudes and behaviours, notably on different dimensions of democratic representation, and with a specific focus on democratic resentment (e.g. citizens' attitudes towards democracy such as distrust and alienation, but also behaviours such as abstention, protest, or voting for anti-establishment parties). Its longitudinal structure allows to explore the political dynamics at play in Belgium throughout the lengthy government formation process. Finally, the last two waves of the RBP were fielded during the Covid-19 pandemic, allowing to explore public opinion before and during this global crisis. The RBP should be of interest to scholars of public opinion and electoral studies. © 2023, The Author(s).
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[...]to ensure a safe re-opening of the unit in alignment with rules set by the government, regulatory authorities, local hospitals, the local ethics committee and SGS's company policy, a COVID-19 risk implementation plan was created. Following evaluation, bed capacity was reduced by 20 beds, and plastic screens were put in place where applicable. [...]the number of monitors, visits, and the length of time in the monitoring room is limited to a minimum.
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As online learning becomes a recurrent component of higher education, there have been growing interests in the interaction between students and educational resources within digital environments so as to understand and facilitate students' initiative in managing those resources. The present study is an explorative inquiry into the relationships between students' self-reported preferences of study materials, their actual usage of those materials and their learning performances in online learning. It focuses on analysing the learning management system's log files, test results and students' responses to an evaluative survey of a bachelor business course at a large Belgian university, which was a blended course turned fully online due to the pandemic circumstance. The first research question concerns how preferences relate to the usage of materials. A cluster analysis was conducted to classify students based on their perceived interest and actual access to learning resources. The results show three clusters of students with different preferences and levels of usage towards the four types of study materials provided in the course. However, the majority showed strong favour for multimedia online learning, with Web lectures being prioritised both in perception and access behaviour, while discussion boards receive mixed opinions and the lowest actual participation. The second question follows these up by linking the preference-usage patterns with academic performances. A multivariate analysis of variance was conducted to compare the learning performances of students with different preference-usage patterns. The results show no significant differences, which means the students' preferences and/or usage of study materials has little to no impact on their learning performances in the online course.
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Background: Little is known about the impact of the COVID-19 pandemic on physiotherapists' mental health. The aim of this study was to investigate the impact of the COVID-19 pandemic on physiotherapists' mental health in Belgium. Method(s): A total of 115 physiotherapists from 12 general hospitals in Brussels, working in COVID-19 care units (CCU) or non-COVID-19 care units (NCCU), participated in an electronic survey including validated measurement tools for PTSD, anxiety, insomnia and burnout. Descriptive analyses were performed to assess differences in mental health outcomes between physiotherapists who worked in a CCU and those who worked in an NCCU. Multivariable logistic regression analyses were also performed to assess risk factors for burnout. Result(s): Results showed significant levels of PTSD (9.6%), anxiety (33.9%), insomnia (40%) and burnout (33.9%) among participants. However, no significant differences were found between the 2 groups. It was also found that being isolated during the COVID-19 pandemic was a risk factor for burnout. Conclusion(s): Although no significant differences were found between the two groups, this study highlights a concerning rate of psychopathological symptoms among participants. Hospitals should therefore invest more time and resources into actions aiming at preserving the mental health of physiotherapists.Copyright © 2023 Informa UK Limited, trading as Taylor & Francis Group.
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[...]countries do not always recognize and allow electronic signatures. In many cases, this calls for a complete revision of existing laws and regulations;it has already been done in the past for some technologies, including the regulation of electronic signatures, but much more important revisions, such as the third revision of International Conference on Harmonization Good Clinical Practice (ICH GCP), are underway for the complete integration of the various aspects of emerging technologies.7 In the scope of our research project, titled "Toward a Global Implementation of eConsent in Clinical Trials," a survey was conducted to understand how eConsent is perceived and experienced by clinical research experts, how it can improve patient comprehension and reduce site burden, as well as to identify areas of opportunities and challenges for further adoption. [...]when stakeholders were asked what the main barrier limiting the implementation of eConsent at their organization is, many sponsors explained that the fragmented guidelines and regulations had considerably hindered their use of eConsent. [...]it requires staff training and adaptation and, here again, the fragmented or-in some cases-even lack of regulation around eConsent makes it difficult to implement on sites.
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This chapter focuses on how the executives have adapted to the pandemic challenge since March 2020. To do so, it develops a comparative analysis of the role of the executives in facing the COVID-19 pandemic in three selected European jurisdictions, namely, Belgium, Germany, and Italy. An underlying assumption in this chapter is that executives, more or less inevitably, are crucial actors in major crises;still, it remains to be seen how these very crises impact on their structure and functioning. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
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Objectives: To evaluate the ECMO offer during the COVID pandemic in the different European countries Methods: We colected COVID and demographic data from Worldometer and the national ECMO runs from the EuroELSO platform. Result(s): Europe presented a broad offer of ECMO. If during the first wave the Health System;s resources were not prepared to accommodate the high number of patients, during the following two years ECMO demonstrated to be a useful tool in the treatment of COVID pneumonia. However, across different European countries the use of ECMO was very different. In Portugal ECMO was used in 336 patients, in a universe of 5,557,941 COVID cases within a total population of 10,140,570 individuals. Of these, 336 were placed on extracorporeal circulation, which corresponds to 60.5 cases per million positive cases and 33.1 per 1 million individuals. The average number of patients placed on extracorporeal membrane oxygenation (ECMO) per million positive cases was 39 amongst the surveyed countries. Portugal was the 4th country with the most patients of ECMO per million cases (1st is Belgium with 106.5;Estonia 106.1;and Austria 68.5) and per million inhabitants (33.1), after Estonia (49.2), Austria (43.2) and Belgium (42.6). The mortality rate of COVID patients in Portugal is 0.46%. It is lower than the average of the countries under analysis (0.56%). When analyzing the frequency of cases concerning the mortality rate, there is seemingly an increase in the mortality rate with a decrease in the number of cases. The significant differences in the mortality rate between different countries can be explained by several other factors: different criteria for the main diagnosis of death;capacity of the different countries regarding the population;s access to vaccination and the different access to health care. Conclusion(s): ECMO-COVID offer was very different across countries. In Portugal, the offer was amongst the greatest in Europe, not compromising the overall response to the global COVID population.
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Following a COVID-19 outbreak in an elderly-care home in Belgium by winter/2020, an assessment of the ventilation conditions at said care home was conducted in summer/2021. Four common-rooms were selected as the most-likely involved in the outbreak and assessed via (artificially-injected) CO2-decay test for average air change rates (ACHs) measurement. Two of the rooms were also assessed via passive tracer gas test for long-term ACHs measurement, using decane-D22 as tracer. The average ACHs measured (via both methods) ranged from 1, 8 to 3, 6 h-1 in summertime, being thus probably higher than the ACHs during the outbreak. Nevertheless, none of the ACHs measured comply with the latest recommendations for COVID-19 prevention. Ventilation grilles and decentralized ventilation systems in common areas could enhance the building's ventilation, but thoughtful installation is essential;experience shows that thermal discomfort often leads to closing ventilation grilles even during a pandemic, resulting in significantly diminished fresh-air supply. © 2022 17th International Conference on Indoor Air Quality and Climate, INDOOR AIR 2022. All rights reserved.
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Intro: The burden of infectious diseases is influenced by the structure of the population at risk. Population ageing may have implications for the disease burden of future epidemics. Moreover, changing household structures induced by population ageing may influence the dynamics of disease transmission and burden of infections transmitted via close contact interactions. We aim to investigate the impact of demographic change on the disease transmission dynamics and future disease burden and illustrate this for COVID-19 and influenza-like illness (ILI). Method(s): We simulate the Belgian population between 2020 and 2050 using an individual-based model with census data. The simulated population structures were used as input for an infectious disease model that distinguishes between exposure to infection in the household versus exposure in the community at large. We mimicked outbreaks of COVID-19 and ILI of varying total final size. Finding(s): The simulated population ages between 2020 and 2050, which also affects household size and composition. As the proportion of elderly people in the population increases, the overall attack rate slightly decreases because older age groups have fewer contacts and are therefore less likely to incur and transmit infections. Despite the lower per-person attack rate, the estimated disease burden increases as morbidity and mortality increases with the age at infection. Conclusion(s): The demographic changes induced by population ageing have an impact on the burden of future outbreaks of COVID-19 and ILI in Belgium. The shifting age distribution implies that the elderly, a population group with increased morbidity and mortality in case of infection, make up an increasing proportion of the total population. Population ageing also leads to an increasing proportion of single-person households and collective households (e.g. nursing homes) in the population. Since the household attack rate varies by household size and composition, the living arrangements of the elderly population influences the disease burden of future epidemics to some extent.Copyright © 2023
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BACKGROUND: To protect school-aged children from the potential consequences of a new viral infection, public health authorities recommended to implement infection prevention and control (IPC) measures in school settings. Few studies evaluated the implementation of these measures and their effect on SARS-CoV-2 infection rates among pupils and staff. The aim of this study was to describe the implementation of infection prevention and control (IPC) measures in Belgian schools and assess its relation to the prevalence of anti-SARS-CoV-2 antibodies among pupils and staff. METHODS: We conducted a prospective cohort study in a representative sample of primary and secondary schools in Belgium between December 2020 and June 2021. The implementation of IPC measures in schools was assessed using a questionnaire. Schools were classified according to their compliance with the implementation of IPC measures as 'poor', 'moderate' or 'thorough'. Saliva samples were collected from pupils and staff to determine the SARS-CoV-2 seroprevalence. To assess the association between the strength of implementation of IPC measures and SARS-CoV-2 seroprevalence among pupils and staff, we conducted a cross-sectional analysis using the data collected in December 2020/January 2021. RESULTS: A variety of IPC measures (ventilation, hygiene and physical distancing) was implemented by more than 60% of schools, with most attention placed on hygiene measures. In January 2021, poor implementation of IPC measures was associated with an increase in anti-SARS-CoV-2 antibody prevalence among pupils from 8.6% (95%CI: 4.5 - 16.6) to 16.7% (95%CI: 10.2 - 27.4) and staff from 11.5% (95%CI: 8.1 - 16.4) to 17.6% (95%CI: 11.5 - 27.0). This association was only statistically significant for the assessment of all IPC measures together in the population comprised of pupils and staff. CONCLUSIONS: Belgian schools were relatively compliant with recommended IPC measures at the school level. Higher SARS-CoV-2 seroprevalence among pupils and staff was found in schools with poor implementation of IPC measures, compared to schools with thorough implementation. TRIAL REGISTRATION: This trial is registered under the NCT04613817 ClinicalTrials.gov Identifier on November 3, 2020.
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COVID-19 , Child , Humans , Antibodies, Viral , Belgium/epidemiology , COVID-19/epidemiology , COVID-19/prevention & control , Cross-Sectional Studies , Prospective Studies , SARS-CoV-2 , Seroepidemiologic StudiesABSTRACT
Objectives: An exceptional effort by the scientific community has led to the development of multiple vaccines against COVID-19. Efficacy estimates for these vaccines have been widely communicated to the general public, but are nonetheless challenging to compare because they are based on phase 3 trials that differ in study design, definition of vaccine efficacy and the handling of cases arising shortly after vaccination. We investigate the impact of these choices on vaccine efficacy estimates, both theoretically and by re-analyzing the Janssen and Pfizer COVID-19 trial data under a uniform protocol. We moreover study the causal interpretation that can be assigned to per-protocol analyses typically performed in vaccine trials. Finally, we propose alternative estimands to measure the intrinsic vaccine efficacy in settings with delayed immune response. Methods: The data of the Janssen COVID-19 trials were recreated, based on the published Kaplan-Meier curves. An estimator for the alternative causal estimand was developed using a Structural Distribution Model. Results: In the data analyses, we observed rather large differences between intention-to-treat and per-protocol effect estimates. In contrast, the causal estimand and the different estimators used for per-protocol effects lead approximately to the same estimates. Conclusions: In these COVID-10 vaccine trials, per-protocol effects can be interpreted as the number of cases that can be avoided by vaccination, if the vaccine would immediately induce an immune response. However, it is unclear whether this interpretation also holds in other settings.
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Background: The New Global Economy is represented by a series of major features, such as the use of green energy, the reduction of the carbon footprint in all industrial and civil fields, as well as finding alternative food resources. Our main objective was the research of a sustainable food product with a special nutritional purpose in the vision of nutrivigilance, developed in Romania, as an adjuvant in the repair of gastric mucosa. Methods: The materials used in the research and development of the new food are the following: inulin, lactoferrin, sericin, and sodium bicarbonate. The new adjuvant food product in the repair of the gastric mucosa was added to certain foods in order to prevent the patients from being satiated by a single food from a sensory point of view. The resulting food products were organoleptically and physico-chemically analyzed. Results: The new food is sustainable and has versatile uses. It can be hydrated with water, non-carbonated drinks, mixed with cottage cheese, or with fruit puree and oatmeal. It is stable under normal storage conditions and microbiologically safe. Conclusions: Through its versatile use, the new food product for special nutritional conditions represents a worldwide novelty. Through the development of forestry for the cultivation of white or black mulberry (Morus alba and Morus nigra), the raising of silkworms (Bombyx mori), the processing of fibroin to obtain natural silk and the processing of sericin resulting as a residue in the textile industry, the new food product developed actively contribute to the global economy II.
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This seminal study examines how Taiwanese immigrants make friends and their convivial experiences interacting with social others in the host society in Belgium. In this study, the author successfully recruited 24 Taiwanese immigrant restaurateurs and housewives to participate in semi-structured interviews during the author's three years of fieldwork as the Chinese language and cultural courses teacher at the Ecole Sun Yat Sen Brussels. The study finds that sharing foods with others is one of the important friendshipmaking strategies in migrants' everyday life. In so doing, food does not only provide its material and nutrition functions, but it also makes many social meanings and functions for people who participate in activities and assist them to obtain sense of belonging, group identity and emotional support. In addition to food sharing, social media use is another vital tool for Taiwanese immigrants to make friends and cultivate their social networks living in a foreign country. However, a significant difference in using social media in making friends exists between different genders and age generations. With regard to convivial experiences, most of the research participants had positive experiences interacting with locals and social others before the COVID-19 pandemic. As they successfully accumulated such convivial experiences, these experiences, in turn, helped them construct a cosmopolitan identity and improve their personal inter-cultural competences. However, after the pandemic has worsened, Taiwanese immigrants have faced discriminations due to their race and migrant backgrounds more frequently. On the contrary, the frequencies of convivial interactions between Taiwanese immigrants with locals and social others have obviously decreased because of the pandemic. Notably, although Taiwanese immigrant restaurateurs and housewives may have different experiences and practices in making friends, they have similar social network characteristics as they have more intra-ethnic than interethnic friends and social ties. In addition, the limitations of the study and the suggestions for further research will also be discussed in the article. © 2022, City University of Hong Kong Press. All rights reserved.
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Background: Adults living with HIV may have higher risk of SARS-CoV- 2 infection than HIV negative adults. There are no published data on seroprevalence of SARS-CoV-2 in children and adolescents living with HIV (CALWHIV). Method(s): We did a repeat SARS-CoV-2 seroprevalence study in 7 paediatric HIV observational cohorts in 5 countries in the European Pregnancy & Paediatric Infections Cohort Collaboration (EPPICC;Belgium, Greece, Spain, Ukraine, United Kingdom (UK)) and also the Cape Town Adolescent Antiretroviral Cohort (CTAAC), South Africa (SA) (CALWHIV and HIV negative adolescents). Participants gave 2 blood samples for SARS-CoV-2 antibody testing ~6 months apart during routine visits between May 2020 and July 2022, and completed questionnaires on SARS-CoV-2 exposure/infection and vaccine status. Clinical and demographic data were extracted from clinic records. Result(s): Of 906 participants, 53%(477) were female, 89%(803) CALWHIV, median [IQR] age at first visit 17[15-19] years. Most were enrolled in SA (45%, 410/906), UK (23%, 205/906) or Ukraine (18%, 160/906). 85%(767/906) had 2 blood samples and the rest a single sample. For CALWHIV, at time of first sample, 99%(761/765) were on antiretroviral therapy, median CD4 count was 666[478-858] cells/mL, 70%(535/764) had HIV-1 viral load < 50c/mL. Of those with known SARS-CoV-2 vaccine status, 23%(181/773) CALWHIV and 22% (22/100) HIV negative participants received >=1 vaccine dose. 6%(43/762) of CALWHIV had a documented prior SARS-CoV-2 positive PCR (including 2 hospitalised for COVID, neither severe), and 16%(124/762) self-reported previous positive test and/or COVID-19 symptoms, giving a total of 17%(128/762) with any previous infection. Based on serum testing, 63%(562/898) of participants overall were seropositive on at least one sample (55% (269/488) Europe, 67% (205/307) SA CALWHIV, 85% (88/103) SA HIV negative group), and among the unvaccinated subgroup, 53%(408/765) were seropositive (41% (167/412) Europe, 64% (168/263) SA CALWHIV, 81% (73/90) SA HIV negative). Among samples taken prior to or in absence of vaccination, the proportion testing antibody positive increased over time (Figure). Of unvaccinated CALWHIV with >=1 positive result, 17%(52/299) reported any previous SARS-CoV-2 infection. Conclusion(s): Most CALWHIV were SARS-CoV-2 seropositive by mid-2022 despite low vaccine coverage. Fewer had documented or self-reported COVID-19 infection or disease, suggesting most infections were mild or asymptomatic. Seroprevalence of SARS-CoV-2 antibodies in Europe and South Africa, by HIV status and calendar quarter of sampling. Colours indicate dominant variant based on GISAID data for adults and children.
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The COVID-19 pandemic has highlighted the importance of care, as well as the extent to which it is undervalued in Western societies, emphasising the instrumentalization and neoliberal logic that care is subject to. Since the 1970s, various feminist theorists have developed ethics of care. This evolving and controversial ethic has become a critical tool in sociology, philosophy, economics, and public policy analysis but is still underdeveloped in architecture and urban planning. This paper adopts the feminist ethic of care to analyse and criticise the evolution of a modernist social housing complex. The Cité de Droixhe was built in the 1950s to offer various facilities, 2000 rental social housing units, and vast green areas in Liège (Belgium). However, since its creation, it has undergone major transformations including the demolition of nearly 1000 units. In this qualitative inductive research, an interdisciplinary approach between architecture and social sciences was proposed, combining archival research, semi-structured interviews, and participatory observations. The ethic of care is mobilised both as a research and methodological posture and as an object of analysis. The data collected led to questioning the place of care in the evolution of the large complex under different themes: the facilitation of reproductive work, the valorisation of care professions, and the attention paid to proximity and the daily life of the neighbourhood inhabitants. By highlighting the integration and loss of care within the different transformations of the housing estate, this study shows the importance of reasserting the value of care and making it a collective responsibility, contributing to drawing perspectives for a more feminist, equal, and caring city.
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Introduction: The rapid spread of antimicrobial resistance (AMR), which causes a serious threat to both human health and the global economy, is primarily linked to the overuse and misuse of antibacterial drugs. The AMR crisis is significantly impacted by the use of antibacterial drugs in primary care (1). Within these settings, oral antibacterial drugs are considered one of the most frequently prescribed group of medicines. It has been claimed that within primary care, the proportion of antibacterial drug prescribing is higher outside the regular working hours (out-of-hours (OOH) services) compared to in-hours (IH) services (2). Aim(s): To identify the existing body of literature around oral antibacterial drug prescribing within primary care OOH services. Method(s): The scoping review was guided by the Joanna Briggs Institute manual and reported in accordance with the PRISMA-ScR. Seven electronic databases (Medline, Embase, Emcare, CINAHL, Scopus, Web of Science, and Cochrane Library) were systematically searched, and the results were screened against pre-defined eligibility criteria. Original and secondary analysis studies that addressed oral antibacterial prescribing in OOH primary care and were published in English were included. Titles and s were independently screened by three reviewers. A pre-piloted extraction form was used to extract relevant data. A narrative synthesis approach was used to summarise the results. Result(s): The initial search yielded 834 records. Upon screening, 28 publications fulfilled the eligibility criteria. Included studies originated from nine high-income countries, with the most frequent being the United Kingdom (six studies, 21.4%) followed by Belgium (five studies, 17.9%). Literature on antibacterial prescribing in OOH services was mostly from quantitative studies (23 studies, 82.14%), with only a few employing a qualitative design (five studies, 17.86%). Different themes and sub-themes were identified across these studies. The majority discussed antibacterial prescribing data in terms of the commonly prescribed medications and/or associated conditions. Eleven studies provided a comparison between IH and OOH settings. Seven studies reported the trends of prescribing over time;of these, three explored prescribing trends before and during COVID-19. The impact of intervention implementation on prescribing was investigated in two studies, an educational intervention in one study and the use of an interactive booklet in the other study. Four studies assessed the quality/appropriateness of prescribing either by adherence to guidelines or antibiotic prescribing quality indicators. Limited studies explored prescribing predictors and patients' expectations and satisfaction with OOH services. In contrast, qualitative studies focussed more on exploring prescribers' experiences, perspectives, behaviours, and the challenges they face during consultations within OOH settings which may influence their decision-making process. Of these, one study explored why patients consult OOH services and how they communicate their problems. Conclusion(s): This review shows the key areas around oral antibacterial prescribing in primary care OOH services. While there is a satisfactory number of published articles covering various areas within OOH, the use of different approaches to OOH across countries may confound the comparison of practice. A strength of this work is using three reviewers to screen identified records independently. Further research is needed to provide a better understanding of current practice in these settings and how it may be contributing to AMR.
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Covid-19 lockdowns in many countries were characterised by increases in unpaid labour (e.g. home-schooling), as well as changing working conditions (e.g. remote work). Consequently, a large body of research assesses changes in dual earner couples' gender division of unpaid labour. However, despite the increasingly detailed picture of households' division of labour before and after the onset of the pandemic, it remains unclear how dual earner parents themselves perceive their decision-making regarding labour divisions during lockdowns. Conse-quently, using data from 31 individual in-depth interviews in Belgium, this study adopts a biographical -interpretative method to assess variation in narratives regarding the household division of labour before and during lockdown. Results indicate five ideal type narratives which vary in the extent to which lockdown divisions of unpaid labour exhibit path-dependency or constitute new gender dynamics, but also regarding the balance between individual agency and societal factors as determinants of labour divisions. Taken together, narratives discussing new gender dynamics during lockdowns put forward sector-specific changes in working hours and remote work as external and exogenous determinants. However, most importantly, findings indicate that household decision-making regarding unpaid labour during lockdowns is mostly perceived as path-dependent on pre-covid decision-making (e.g. gender specialisation) in the context of structural (e.g. gendered leave schemes) and normative boundaries (e.g. gendered parenting norms). Such path-dependencies in the decision-making underlying quantitatively identifiable divisions of unpaid labour during lockdowns are likely to be neglected in the absence of a qualitative life course perspective.